QUT offers a diverse range of student topics for Honours, Masters and PhD study. Search to find a topic that interests you or propose your own research topic to a prospective QUT supervisor. You may also ask a prospective supervisor to help you identify or refine a research topic.
Found 2 matching student topics
Displaying 1–2 of 2 results
Understanding the genetics of melanoma susceptibility: many roads lead to DNA repair
Repair of the damage caused by mutagens such as UV and reactive oxygen species is vital to prevent cancer and premature aging and accordingly cells have developed a suite of intricate and specific DNA repair pathways. Loss or abnormal function of components of these pathways lead to cancer pre-disposition syndromes for example breast cancer in individuals carrying mutations in the BRCA1 or BRCA2 genes. Understanding the complexities of these DNA repair pathways is vital to efforts aimed at preventing or …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
Dissecting the molecular and cellular basis of melanoma susceptibility
Several factors strongly influence an individual’s chance of developing melanoma. Paramount amongst these are the number of moles (nevi) present on the skin, cumulative levels of UV exposure and skin pigmentation phenotype. Numerous Genome Wide Association Studies (GWAS) we have identified gene variants at a number of loci that are strongly associated with cutaneous nevi (mole) counts, UV damage response and accordingly susceptibility of individuals to develop melanoma. Currently the functional impact of genetic variants in the genes IRF4, PLA2G6 …
- Study level
- Master of Philosophy, Honours
- Faculty
- Faculty of Health
- School
- School of Biomedical Sciences
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